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LIMITED EDITION
Summer-proof your collagen. Future-proof your skin.
Save 15% on exclusive new sets built to address the visible signs of collagen loss and UV aging.
Limited Edition
Face
Body
Sets
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FACE LONGEVITY DEFENSE DUO
4.7
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4.5
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OS-01 FACE SPF 30+
4.6
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HEAD-TO-TOE SKIN HEALTH TRIO
4.7
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4.5
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FACE LONGEVITY DEFENSE DUO
4.7
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BODY LONGEVITY DEFENSE DUO
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4.5
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LONGEVITY ESSENTIALS TRIO
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OUR APPROACH
Led by science, not hype
Rigorous R&D platform
End-to-end product development run by our in-house team of scientists.
Scientifically validated claims
Quantified by our proprietary MolClock and Skin Age Modeling methods.
Ongoing clinical studies
Conducted by independent, third-party research organizations.
Peer-reviewed publications
The gold standard for scientific research and in skin care.
OUR APPROACH
The real proof? It’s in the numbers.
9 years of research
900 peptides screened
22 patents & publications
12000 5-Star Reviews
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OUR BREAKTHROUGH PEPTIDE
OS-01: the new standard in peptide technology
Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t. 01
6 visible signs of senescence
Lines and wrinkles
Caused by a decline in collagen and elastin production.
Loss of elasticity
Decreased elastin also contributes to lack of firmness.
Uneven skin tone
Irregular melanin production leads to hyperpigmentation.
Rough texture
Compromised skin cell renewal leaves a dry, uneven surface.
Loss of volume
Linked to a decrease in hyaluronic acid, collagen, and elastin.
Thinning skin
Slower cell turnover contributes to a weakened skin barrier.
DAILY ESSENTIALS
The 5-minute skin health routine
PREP Cleanser
OS-01 EYE
OS-01 FACE
OS-01 FACE SPF
Gently cleanse and exfoliate without irritation
Support delicate skin with the highest concentration of OS-01
A daily longevity serum and lightweight moisturizer in one
Repair UV aging while protecting against new UV-damage01
\ \ Explore our peer-reviewed research\ \ Check out the data](/content/pages/scientific-publications/index.html)
\ \ The brains behind the breakthrough\ \ Meet the founders](/content/pages/our-story/index.html)
The Reference Lab
\ \
- SKIN CARE\ \ Not All Peptides Are Created Equal](/content/blogs/reference-lab/not-all-peptides-are-created-equal/index.html)
\ \
- ONESKIN PRODUCTS\ \ Behind the Seal: How OneSkin Achieved the National Eczema Association's Seal of Acceptance](/content/blogs/reference-lab/oneskin-has-earned-the-national-eczema-associations-seal-of-acceptance/index.html)
\ \
- LONGEVITY\ \ Skin Care is Health Care: Why Skin Care is the Key to Longevity](/content/blogs/reference-lab/skin-care-is-health-care-why-extending-your-skinspan-is-key-to-longevity/index.html)
\ \
- INGREDIENTS\ \ Peptides Vs Growth Factors: Which is Better For Skin Longevity?](/content/blogs/reference-lab/peptides-vs-growth-factors-which-is-better-for-skin-longevity/index.html)
Frequently Asked Questions
What are peptides?
Peptides are short chains of amino acids. They represent a broad class of molecules with many jobs, from forming the building blocks of larger proteins to acting as cellular messengers. Peptides found naturally in the body (called endogenous peptides), play a crucial role in tissue growth, hormone regulation, and other biological processes. Exogenous peptides, which can be injected, ingested or delivered topically like OS-01, can send out signals to skin cells to trigger collagen and hyaluronic acid production, aid in cellular repair, and help strengthen the skin barrier.01,02,03
How does OS-01 work?
OS-01 reduces the accumulation of senescent cells. These cells release inflammatory chemicals that cause neighboring cells to become dysfunctional, kicking off a domino effect in skin and accelerating skin aging. By reducing this inflammatory response, OS-01 helps prevent the accumulation of senescent cells in skin, improving key skin aging biomarkers and keeping other skin cells healthy and thriving.01,02,03
Who is OneSkin for?
OneSkin is for everyone. Whether you’re taking a preventative approach or want your skin’s health and appearance to reflect how you feel on the inside, our scientifically proven products work at the cellular level to keep your skin looking, feeling, and acting younger and healthier as you age.01,02,03
What skin concerns does OneSkin address?
Through lab studies and clinical studies, our products have been shown to combat the visible and invisible signs of aging, from collagen loss and thinning skin to a compromised barrier function.01,02,03
To learn more about the specific benefits of each product, visit oneskin.co/claims.
How long does it take to see results?
With daily use, you can expect to see visible results within 12 weeks, though some people see changes even sooner. This time frame allows OS-01 to work at the cellular level, improving the long-term health and appearance of your skin.01,02,04
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi: 10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi: 10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at [oneskin.co/claims](/content/claims "View the OneSkin Claims"/index.html) 04 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi: 10.1111/ics.13042
PHILANTHROPY
Propelled by a shared mission to change the way humans experience aging
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We donate a portion of sales to the Aging Forward (formerly Shepherd's Center of America), which provides enriching opportunities for lifelong learning, volunteer service, healthy living, and community connections - all of the things that give life meaning.
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