OS-01 BODY MOISTURIZER – OneSkin
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OS-01 BODY MOISTURIZER
4.7
4.7 out of 5
250 mL / 8.45 fl oz
OS-01
BODY MOISTURIZER
4.7★ (3,680 reviews)
Addresses dry, crepey skin at the cellular level.
Clinically studiedBarrier-buildingFragrance-free
Clinicians'
Choice
262 clinicians,
& dermatologists
share this product
on FrontrowMD.
Learn more
Read their reviews
Clinicians'
Choice
262 clinicians,
& dermatologists
share this product
on FrontrowMD.
Learn more
Read their reviews
OS-01
BODY MOISTURIZER
Addresses dry, crepey skin at the cellular level.
4.7
4.7 out of 5
4.7
4.7 out of 5
250 mL / 8.45 fl oz
Clinically studiedBarrier-buildingFragrance-free
Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM and OneSkin Longevity ScienceTM.01
Improves skin texture, appearance, and hydration
Strengthens the skin barrier by up to +41%
Dermatologist tested, fragrance-free, safe for sensitive skin
One-time purchase
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LIMITED TIME OFFER
Travel-size OS-01 EYE with your first subscription
$38FREE
Delivered every month
$105$90
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- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
Recommended
Delivered every 2 monthsRecommended
$105$90
Subscribe and save 15%
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
LIMITED TIME OFFER
Travel-size OS-01 EYE with your first subscription
$38FREE
One-time purchase
$105
Quantity
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ADD TO CART $105$90
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Details−
- A daily body moisturizer powered by the OS-01 Peptide™.¹ Engineered to address a key driver of visible skin aging.²
- Fast-absorbing, never greasy. 93% of users reported improved hydration in 12 weeks.¹
- Clinically proven to strengthen the skin barrier by up to +41% in 12 weeks.¹ A stronger barrier supports every step of your longevity routine.
Clinical proof+
A 12-week, third-party clinical study demonstrated OS-01 BODY significantly improves skin hydration (+38%), barrier strength (+41%), and texture. Published in the Journal of Cosmetic Dermatology.
Explore the clinical studies →
Ingredients+
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs.
Ingredients
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol.
*OS-01 Peptide
How to use+
Massage a generous amount into any area of the body: arms, legs, chest, décolleté, hands, and neck. Use morning and night.
Complete the protocol
OS-01 FACE MOISTURIZER
★★★★★4.8
Your daily investment in firmer, smoother, more resilient skin.
ADD TO CART — $117
OS-01 EYE CREAM
★★★★★4.8
Firm and hydrate the delicate skin around the eyes.
ADD TO CART — $109
Clean + Safe Ingredients
Our products are non-comedogenic (non pore-clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents. We prioritize the use of key ingredients that ensure a safe and effective formulation, delivering the best results for your skin needs.
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BENEFITS
Nourishing body moisturizer and targeted treatment for thin, crepey skin
Smooth texture
Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01
Deep hydration
Replenishes and locks in hydration to keep skin soft, plump, and nourished.01
Barrier support
Fortifies the skin barrier to protect against daily stressors and moisture loss.01
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5-STAR REVIEWS
See why customers love OS-01 BODY
“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.
"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.
"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
93 of participants reported improved hydration 01
70 of participants reported improved appearance 01
70 of participants reported improved texture 01
41 Improvement in skin barrier function was measured 01
5 active ingredients complement the OS-01 peptide
Tremella Fuciformis Sporocarp Mushroom extract
This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.
Ceramides
Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.
Sulforaphane
Found in Lepidium Sativum Sprout Extract, this antioxidant has potent antimicrobial and anti-inflammatory properties.
Saccharide isomerate
A prebiotic shown to support the healthy bacteria on skin.
Genistein
A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.
Note: Due to the natural oils used in our formulas, the scent of the product may vary.
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Getting started with OS-01 BODY
Follow these easy steps for optimal results
- Apply to arms, legs, chest, back, and stomach
- Massage until absorbed
- Use 2 times daily
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How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.02,03
All Ingredients
Citations
01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi: 10.1038/s41514-023-00109-1
03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi: 10.1186/s13148-020-00899-1
Dr. Donna Hepper, MD
Verified clinician
Specialty
Dermatology
Years in practice
19
Reinforces the skin barrier with OS-01 peptide and ceramide NP
Crinkly-looking skin or roughness can signal the need for care that goes beyond surface moisture, which is why I appreciate this body moisturizer. Along with plant-derived moisturizers, it contains ingredients that may strengthen the skin barrier. Without a strong barrier, skin can lose moisture more easily, leading to that paper-thin, crinkled appearance. The key ingredient, OS-01, is included to help support the skin barrier, and I like that it's paired with ceramide NP. Ceramides are lipids that fill the spaces between skin cells, and this type may reinforce the skin's outer layer. Together, these ingredients may moisturize the skin and help it hold onto that hydration. I believe this kind of support can benefit mature skin, though I'd happily recommend it for any stage of adult life.
†
International Journa... +1
2 Sources
The role of ceramides in skin barrier function and the importance of their correct formulation for skincare applications
International Journal of Cosmetic Science, 2024
Inflammaging and Immunosenescence as Part of Skin Aging—A Narrative Review
International Journal of Molecular Sciences, 2023
Show more
Highlights:Moisturizing ingredientsRetains hydrationSupports mature-skin
†This clinician wants to clarify that larger-scale research to support their product claims is still developing. These statements have not been reviewed by the FDA and are not intended to be medical advice.
OS-01 BODY MOISTURIZER
4.7
Rated 4.7 out of 5 stars
Based on 3,680 reviews
5 Rated out of 5 stars
2.9k
Total 5 star reviews: 2.9k
4 Rated out of 5 stars
459
Total 4 star reviews: 459
3 Rated out of 5 stars
190
Total 3 star reviews: 190
2 Rated out of 5 stars
64
Total 2 star reviews: 64
1 Rated out of 5 stars
59
Total 1 star reviews: 59
91% would recommend these products
Reviews 3,680(tab expanded) Questions 51(tab collapsed)
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3,680 reviews
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- SG
Sarah G.
Verified Buyer
Reviewing
OS-01 BODY MOISTURIZER
I recommend this product
Rated 5 out of 5 stars
3 minutes ago
Perfect for summer!
First time trying the Body Moisturizer and am loving it for my dry Idaho summer! Will be buying again.
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- C
Cynthia
Reviewing
OS-01 BODY
I recommend this product
Rated 5 out of 5 stars
Yesterday
5 Stars
Love it , nice and light but bery good coverage . Time will tell but so far so good!
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Yes, this review from Cynthia was helpful. 0 people voted yesNo, this review from Cynthia was not helpful. 0 people voted no
- T
Tyger
Reviewing
OS-01 BODY MOISTURIZER
I do not recommend this product
Rated 2 out of 5 stars
Yesterday
2 Stars
I realized the ounces on purchase, but unless it performs miracles, I can’t afford this small size for that price.
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- SS
Stephanie S.
Verified Buyer
Reviewing
OS-01 BODY MOISTURIZER
I recommend this product
Rated 5 out of 5 stars
Yesterday
Best skin ever
I will be using this more consistently as i find nothing else helps the skin every where else look and feel moisturized, supple and chase the crepe away! I've been using One Skin on my face for years, i will be using Body moisturizer more now as I get older. Thanks for such helpful products!
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- MS
Maryellen S.
Verified Buyer
Reviewing
OS-01 BODY
I recommend this product
Rated 5 out of 5 stars
Yesterday
Great stuff!!
This is the ONLY body moisturizer that Actuslly made a difference with my crepey skin . I used it everyday for a couple of months and saw a really good change. Much less wrinkly skin and extra soft . I ei from now on only be using this product!!!
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