OS-01 EYE: Peptide Eye Cream | OneSkin
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OS-01 EYE CREAM
4.7
4.7 out of 5
20 mL / .67 fl oz
Clinicians'
Choice
257 clinicians,
& dermatologists
share this product
on FrontrowMD.
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Clinicians'
Choice
257 clinicians,
& dermatologists
share this product
on FrontrowMD.
Learn more
View clinicians
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OS-01 EYE CREAM
Topical Supplement
4.7
4.7 out of 5
20 mL / .67 fl oz
Hydrate and firm ultra-delicate skin with our daily eye cream, formulated with the highest concentration of the OS-01 Peptide™.01
Improves texture, tone, and elasticity
Increase collagen by an average of +130% in lab studies
Dermatologist tested, fragrance-free, safe for sensitive skin
One-time purchase
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LIMITED TIME OFFER
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ADD TO CART - $109$93
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OS-01 EYE CREAMDelivery every 2 months (Most popular)
ADD TO CART - $109$93
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Clean + Safe Ingredients
Our products are non-comedogenic (non pore-clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents. We prioritize the use of key ingredients that ensure a safe and effective formulation, delivering the best results for your skin needs.
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BENEFITS
Our most potent formula, specially designed for the delicate skin around the eyes, which is prone to accelerated aging 03
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01
Firmness
Supports skin health for a firmer, more lifted appearance.01
Hydration
Strengthens the skin barrier to lock in moisture and keep skin hydrated.01
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5-star reviews
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
96 of participants reported improved texture and tone 01
91 of participants reported improved radiance 01
88 of participants showed improved hydration 01
86 of participants had improved elasticity 01
3 active ingredients complement the OS-01 peptide
Moringa Oleifera Seed extract
Extracted from the seeds of the Moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
Fucus Vesiculosus Algae extract
This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
Biomimetic vegan collagen
This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.
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Getting started with OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone
- Use 2 times daily
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How it works
Powered by the OS-01 Senescence Blocking Peptide™
The first and only peptide scientifically proven to reverse skin’s biological age.05,06
All Ingredients
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi: 10.1111/ics.13042
02 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
03 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
04 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
05 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi: 10.1038/s41514-023-00109-1
06 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi: 10.1186/s13148-020-00899-1
OS-01 EYE CREAM
4.7
Rated 4.7 out of 5 stars
Based on 1,725 reviews
5 Rated out of 5 stars
1.4k
Total 5 star reviews: 1.4k
4 Rated out of 5 stars
183
Total 4 star reviews: 183
3 Rated out of 5 stars
55
Total 3 star reviews: 55
2 Rated out of 5 stars
26
Total 2 star reviews: 26
1 Rated out of 5 stars
24
Total 1 star reviews: 24
94% would recommend these products
Reviews 1,725(tab expanded) Questions 36(tab collapsed)
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1,725 reviews
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- G
Grace
Reviewing
OS-01 EYE CREAM
I recommend this product
Rated 5 out of 5 stars
5 minutes ago
5 Stars
Great eye cream. Absorbs completely around the eye. No stickiness.
Love it
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Yes, this review from Grace was helpful. 0 people voted yesNo, this review from Grace was not helpful. 0 people voted no
- JO
Janine o.
Verified Buyer
Reviewing
OS-01 EYE CREAM
I recommend this product
Rated 5 out of 5 stars
Yesterday
feels great!
I just started using this eye cream this past month, so I can't honestly say I see a difference yet. But I can say if feels wonderful and absorbs into my skin nicely
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Yes, this review from Janine o. was helpful. 0 people voted yesNo, this review from Janine o. was not helpful. 0 people voted no
- VT
victoria t.
Verified Buyer
Reviewing
OS-01 EYE Refill
I recommend this product
Rated 5 out of 5 stars
2 days ago
Love this
Keeps area around eyes well hydrated and soft. Best I’ve ever used.
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Yes, this review from victoria t. was helpful. 0 people voted yesNo, this review from victoria t. was not helpful. 0 people voted no
OneSkin
Yesterday
Hi Victoria! Thank you so much for your wonderful 5-star feedback about OS-01 EYE! We're absolutely thrilled to hear that you're loving it - that kind of enthusiastic response really means the world to all of us at OneSkin!
It's fantastic that the area around your eyes is staying well hydrated and soft, and we're so grateful that you're finding OS-01 EYE to be the best you've ever used! That kind of feedback shows exactly how our science-backed approach to caring for the delicate eye area really delivers real results.
Thank you for taking the time to share such encouraging feedback about your OS-01 EYE experience - your 5-star review truly means so much to us!
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- CT
catherine t.
Verified Buyer
Reviewing
OS-01 EYE Refill
I recommend this product
Rated 5 out of 5 stars
3 days ago
Great
Great
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Yes, this review from catherine t. was helpful. 0 people voted yesNo, this review from catherine t. was not helpful. 0 people voted no
- AF
Angie F.
Verified Buyer
Reviewing
OS-01 EYE CREAM
I recommend this product
Rated 4 out of 5 stars
3 days ago
Eye cream
it feels nice and light and doesn't make my eyes water when I use it.
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Yes, this review from Angie F. was helpful. 0 people voted yesNo, this review from Angie F. was not helpful. 0 people voted no
OneSkin
3 days ago
Hi Angie! Thank you so much for your wonderful 4-star feedback about OS-01 EYE! We're really glad to hear that you're enjoying how light and comfortable it feels - that kind of positive experience really means the world to all of us at OneSkin!
We really appreciate you sharing that the eye cream works so well for your eyes without any irritation. The fact that it feels nice and light while being gentle on your delicate eye area is exactly the kind of everyday performance we hope our customers experience.
Thank you for taking the time to leave a review about OS-01 EYE - your feedback truly means so much to us!
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