HEAD-TO-TOE SKIN HEALTH TRIO – OneSkin

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HEAD-TO-TOE SKIN HEALTH TRIO

4.7

4.7 out of 5

4.7(6,594 reviews)(6.5K)

Full Size

HEAD-TO-TOE SKIN HEALTH TRIO

OS-01 FACE + OS-01 EYE + OS-01 BODY

4.7

4.7 out of 5

4.7(6,594 reviews)(6.5K)

Full Size

Restore your skin’s health with our moisturizers for the face, body, and delicate eye area, powered by the OS-01 PeptideTM.01

One-time purchase

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HEAD-TO-TOE SKIN HEALTH TRIODelivery every 2 months (Most popular)

ADD TO CART - $328$254

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HEAD-TO-TOE SKIN HEALTH TRIO includes:

Clean + Safe Ingredients

Our products are non-comedogenic (non-pore clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents.

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Benefits

Multi-tasking moisturizers that target the signs of aging from head to toe

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.

Texture

Improves the look and feel of thin, crepey skin.

Hydration

Fortifies the skin barrier, allowing for better moisture retention and hydration.

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OS-01 FACE

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

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OS-01 EYE

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.

"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.

"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.

"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

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OS-01 BODY

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.

"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

OUR APPROACH

Results that go beyond the lab

9 Years of Research

900 Peptides Screened

18 Patents & Publications

9000 5-Star Reviews

Active ingredients that complement the OS-01 peptide

Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.

Andiroba oil

A seed oil that promotes healthy collagen and minimizes the effects of inflammation.

Niacinamide

A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.

Oleic Pau Mulato extract

An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.

Allantoin

A skin-conditioning molecule that moisturizes and soothes irritated skin.

Hyaluronic acid

A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.

[See All Ingredients](/content/products/full-size-os-01-face-eye-body-bundle?_ab=0&_fd=0&_sc=1&variant=44686563705091#all-ingredients "#all-ingredients"/index.html)

Extracted from the seeds of the Moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.

Fucus Vesiculosus Algae extract

This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.

Biomimetic vegan collagen

This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.

This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.

Sulforaphane

A potent antioxidant phytonutrient with antimicrobial and anti-inflammatory properties.

Genistein

A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.

Ceramides

Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

Saccharide isomerate

A prebiotic shown to support the healthy bacteria on skin.

OS-01 FACE

Pracaxi oil

Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.

Andiroba oil

A seed oil that promotes healthy collagen and minimizes the effects of inflammation.

Niacinamide

A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.

Oleic Pau Mulato extract

An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.

Allantoin

A skin-conditioning molecule that moisturizes and soothes irritated skin.

Hyaluronic acid

OS-01 EYE

Moringa Oleifera Seed extract

Extracted from the seeds of the Moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.

Fucus Vesiculosus Algae extract

This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.

Biomimetic vegan collagen

OS-01 BODY

Tremella Fuciformis Sporocarp Mushroom extract

This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.

Sulforaphane

A potent antioxidant phytonutrient with antimicrobial and anti-inflammatory properties.

Genistein

A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.

Ceramides

Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

Saccharide isomerate

A prebiotic shown to support the healthy bacteria on skin.

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OS-01 EYE

How to apply OS-01 EYE

Follow these easy steps for optimal results

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OS-01 FACE

How to apply OS-01 FACE

Follow these easy steps for optimal results

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OS-01 BODY

How to apply OS-01 BODY

Follow these easy steps for optimal results

Your browser does not support the video tag.

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How it works

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 02,07

about the science

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi: 10.1038/s41514-023-00109-1

03 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi: 10.1111/jocd.16242

04 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi: 10.1111/ics.13042

05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

07Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi: 10.1186/s13148-020-00899-1

HEAD-TO-TOE SKIN HEALTH TRIO

4.7

Rated 4.7 out of 5 stars

Based on 6,594 reviews

5 Rated out of 5 stars

5.3k

Total 5 star reviews: 5.3k

4 Rated out of 5 stars

771

Total 4 star reviews: 771

3 Rated out of 5 stars

291

Total 3 star reviews: 291

2 Rated out of 5 stars

121

Total 2 star reviews: 121

1 Rated out of 5 stars

116

Total 1 star reviews: 116

92% would recommend these products

Reviews 6,594(tab expanded) Questions 191(tab collapsed)

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6,594 reviews

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Sarah G.

Verified Buyer

Reviewing

OS-01 BODY MOISTURIZER

I recommend this product

Rated 5 out of 5 stars

3 minutes ago

Perfect for summer!

First time trying the Body Moisturizer and am loving it for my dry Idaho summer! Will be buying again.

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Yes, this review from Sarah G. was helpful. 0 people voted yesNo, this review from Sarah G. was not helpful. 0 people voted no

Grace

Reviewing

OS-01 EYE CREAM

I recommend this product

Rated 5 out of 5 stars

Yesterday

5 Stars

Great eye cream. Absorbs completely around the eye. No stickiness.

Love it

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Yes, this review from Grace was helpful. 0 people voted yesNo, this review from Grace was not helpful. 0 people voted no

Cynthia

Reviewing

OS-01 BODY

I recommend this product

Rated 5 out of 5 stars

Yesterday

5 Stars

Love it , nice and light but bery good coverage . Time will tell but so far so good!

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Yes, this review from Cynthia was helpful. 0 people voted yesNo, this review from Cynthia was not helpful. 0 people voted no

Tyger

Reviewing

OS-01 BODY MOISTURIZER

I do not recommend this product

Rated 2 out of 5 stars

Yesterday

2 Stars

I realized the ounces on purchase, but unless it performs miracles, I can’t afford this small size for that price.

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Yes, this review from Tyger was helpful. 0 people voted yesNo, this review from Tyger was not helpful. 0 people voted no

Stephanie S.

Verified Buyer

Reviewing

OS-01 BODY MOISTURIZER

I recommend this product

Rated 5 out of 5 stars

Yesterday

Best skin ever

I will be using this more consistently as i find nothing else helps the skin every where else look and feel moisturized, supple and chase the crepe away! I've been using One Skin on my face for years, i will be using Body moisturizer more now as I get older. Thanks for such helpful products!

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Yes, this review from Stephanie S. was helpful. 0 people voted yesNo, this review from Stephanie S. was not helpful. 0 people voted no

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