OS-01 LIP MASK – OneSkin
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OS-01 LIP MASK
4.5
4.5 out of 5
7 mL / 0.24 fl oz
OS-01
LIP MASK
4.5★ (326 reviews)
An overnight lip mask for visibly smoother, fuller lips over time.
Collagen-boostingOvernight repairFragrance-free
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OS-01
LIP MASK
An overnight lip mask for visibly smoother, fuller lips over time.
4.5
4.5 out of 5
4.5
4.5 out of 5
7 mL / 0.24 fl oz
Collagen-boostingOvernight repairFragrance-free
STARTER SET\ \ 7 mL / 60 uses per bottle REFILL\ \ 7 mL / 60 uses per pod
A deeply hydrating overnight lip mask powered by the OS-01 Peptide™ to restore smoother, fuller, healthier lips.01
Stimulates collagen, elastin, and hyaluronic acid production
98% agreed their lips stayed hydrated for 8+ hours; 81% saw fewer wrinkles around the lips
Dermatologist tested, fragrance-free, safe for sensitive skin
*Applies clear. Due to natural ingredients, color in compact may vary slightly.
One-time purchase
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$42$36
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Details−
- Powered by the proprietary OS-01 Peptide™, works where lip aging begins for lips that look and feel smoother, fuller, and healthier over time.
- Rich, non-sticky, and fragrance-free — an overnight formula that melts into lips and works while you sleep.
- Clinically shown to deliver visibly smoother, fuller lips with improved collagen and elastin production in 4 weeks.¹
- Outperforms leading peptide lip treatments and an award-winning lip mask on collagen and elastin biomarkers.²
Clinical proof+
A 12-week consumer perception study demonstrated OS-01 LIP significantly improves lip hydration (98%), smoothness (97%), and reduces fine lines (87%). In lab studies, OS-01 LIP increased collagen biomarkers by +138%.
Ingredients+
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs.
Ingredients
Ricinus Communis (Castor) Seed Oil, Hydrogenated Vegetable Oil, Octyldodecanol, Diisostearyl Malate, Squalane, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Butter, Euphorbia Cerifera (Candelilla) Wax, Cera Alba (Beeswax), Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Haematococcus Pluvialis Extract (Astaxanthin), Phaeodactylum Tricornutum Extract, Tocopherol, Palmitoyl Hexapeptide-12, Decapeptide-52*, Rosa Canina (Rosehip) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Bisabolol, Allantoin, Silica, Tocopheryl Acetate, Caprylhydroxamic Acid, Caprylyl Glycol.
*OS-01 Peptide.
How to use+
Apply a generous layer to clean lips and the lip border each night before bed.
Complete the protocol
OS-01 FACE MOISTURIZER
★★★★★4.8
Your daily investment in firmer, smoother, more resilient skin.
ADD TO CART — $117
OS-01 LIP SHIELD SPF 15+
★★★★★4.8
Instant hydration and UV defense for vulnerable lips.
ADD TO CART — $30
Clean + Safe Ingredients
Made with vegan, sustainably sourced ingredients. OS-01 LIP Mask is 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents.
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Proven results, backed by real users
After 2 weeks
Lips feel naturally smoother and softer.01
After 2 weeks
Lips feel naturally smoother and softer.01
90%
agree lips feel smoother.
87%
agree lips feel softer.
After 4 weeks
The OS-01 peptide stimulates your natural production of collagen, elastin and hyaluronic acid. Lips feel smoother, softer, and healthier.01
After 4 weeks
The OS-01 peptide stimulates your natural production of collagen, elastin and hyaluronic acid. Lips feel smoother, softer, and healthier.01
81%
who applied OS-01 LIP around their lip border reported reduced fine lines and wrinkles around their lips. (n=32)
90%
agree lips retain hydration for longer.
After 8 weeks
Lips continue to experience improvements in fullness, less fine lines and wrinkles, and overall appearance.01
After 8 weeks
Lips continue to experience improvements in fullness, less fine lines and wrinkles, and overall appearance.01
97%
agreed lips feel healthier.
88%
agreed the overall appearance of lips improved.
After 12 weeks
Lips look noticeably younger and feel more resilient and hydrated.01
After 12 weeks
Lips look noticeably younger and feel more resilient and hydrated.01
97%
agreed lips feel smoother.
87%
reported reduced fine lines and wrinkles on their lips.
2 WEEKS4 WEEKS8 WEEKS12 WEEKS
Ingredients that complement the OS-01 Peptide™
Microalgae
Rich in omegas and carotenoids to help soothe and revitalize stressed or sensitive skin.
Ceramides and squalane
Naturally derived biomimetic lipids that reinforce the lips’ protective barrier.
Astaxanthin
A super-antioxidant from algae, up to 6,000x stronger than vitamin C, that gives the formula its color and helps lips look firmer and smoother.
Palmitoyl hexapeptide-12
A secondary peptide that works synergistically with OS-01 to support firmer, more resilient lips.
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How to apply OS-01 LIP
Using the metal applicator, apply a generous layer onto clean, dry lips as needed.
For a deep treatment, apply before bed and leave on overnight.
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HOW OS-01 WORKS
The science to unlock your healthiest skin
Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02
OS-01 is scientifically proven to:
- Support repair by reducing the buildup of senescent “zombie” cells
- Improve how skin behaves, stimulating collagen and hyaluronic acid production
- Build resilience, keeping your skin healthy and youthful as you age
Full ingredient list
Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 PeptideTM
Your OS-01 LIP questions answered
What is the difference between OS-01 LIP and OS-01 LIP SPF?
OS-01 LIP SPF is your daytime defense, powered by non-nano zinc oxide to protect against UV damage—one of the biggest accelerators of lip aging. It also targets oxidative stress and cellular aging to help maintain your lips’ natural volume and resilience.
OS-01 LIP Mask is your nighttime restoration treatment, designed to work with your skin’s peak repair window at night. Powered by the OS-01 Peptide™, it helps stimulate your skin’s natural production of collagen for fullness, hyaluronic acid for hydration, and elastin for smoothness.
Used together, they provide 24-hour cellular support for your most vulnerable skin.
[**Check out the OS-01 LIP Duo**](/content/products/lip-duo "OS-01 LIP Duo"/index.html)
Does OS-01 LIP have any scent or flavor?
No, OS-01 LIP is fragrance and flavor free. It is tasteless, goes on clear, and any scent comes from the natural ingredients.
Can OS-01 LIP be used during the day?
Yes! While we designed OS-01 LIP SPF to be used during the day due to its environmental and UV protection, OS-01 LIP can be used anytime your lips need extra hydration. We always recommend SPF protection during the day.
Is OS-01 LIP easily absorbed, or will it stay on top of the lips?
OS-01 LIP will absorb into the lips. Due to its rich formula your lips will still appear hydrated, but not shiny.
How do I wash the applicator?
We recommend giving it a quick rinse with soap and water, or using an alcohol wipe to clean when needed.
OS-01 LIP MASK
4.5
Rated 4.5 out of 5 stars
Based on 326 reviews
5 Rated out of 5 stars
248
Total 5 star reviews: 248
4 Rated out of 5 stars
25
Total 4 star reviews: 25
3 Rated out of 5 stars
23
Total 3 star reviews: 23
2 Rated out of 5 stars
18
Total 2 star reviews: 18
1 Rated out of 5 stars
12
Total 1 star reviews: 12
84% would recommend this product
Reviews 326(tab expanded) Questions 10(tab collapsed)
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326 reviews
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- R
Randi
Reviewing
OS-01 LIP MASK
I recommend this product
Rated 5 out of 5 stars
16 hours ago
5 Stars
Feels great
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Was this helpful?
Yes, this review from Randi was helpful. 0 people voted yesNo, this review from Randi was not helpful. 0 people voted no
- SK
Susan K.
Verified Buyer
Reviewing
OS-01 LIP MASK
I recommend this product
Rated 5 out of 5 stars
21 hours ago
Lip Mask
Love this mask!! Makes lips smooth and moisturized!
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Was this helpful?
Yes, this review from Susan K. was helpful. 0 people voted yesNo, this review from Susan K. was not helpful. 0 people voted no
- MA
Mary A.
Verified Buyer
Reviewing
OS-01 LIP MASK
I recommend this product
Rated 5 out of 5 stars
3 days ago
BEST Anti Aging Lip Mask
I admit, I was VERY skeptical but at 59 years of age I am anting to look my best and figured this was worth a try. This product is the BEST anti aging lip product I have ever used. It has filled in a few vertical lip lines around my lips simply by plumping my lips themselves. It is a very subtle difference but definitely noticeable. I was reluctant to invest in such an expensive lip mask but it is now on subscription and I am trying their entire skincare line for anti aging because menopause is very hard on the skin and I want to look my best at every age.
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Yes, this review from Mary A. was helpful. 0 people voted yesNo, this review from Mary A. was not helpful. 0 people voted no
- KD
Kimberly D.
Verified Buyer
Reviewing
OS-01 LIP MASK
I recommend this product
Rated 4 out of 5 stars
3 days ago
Fabulous Formula
I’ve been using this product for about two weeks and, although I have not seen visible changes, it feels fabulous on. I’m a self professed, lip treatment junky and this, by far, exceeds my expectations and is heads and shoulders above much I have used. I love the silky, thickness of the product which is still on in the morning. Truly, the only reason I’ve rated this 4 stars is the applicator. I understand the concept and it does feel nice on the lips, but it’s too small to effectively hold in your fingers. Something that has a longer handle and more “paddle” shaped would be more efficient. I try to make it work :)
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Yes, this review from Kimberly D. was helpful. 0 people voted yesNo, this review from Kimberly D. was not helpful. 0 people voted no
OneSkin
2 days ago
Hi Kimberly! Thank you so much for your wonderful 4-star feedback about OS-01 LIP MASK! We're absolutely thrilled to hear that you're loving how the formula feels on your lips - that kind of positive experience from a self-professed lip treatment junky really means the world to all of us at OneSkin!
We really appreciate your thoughtful feedback about the silky thickness and how beautifully it stays on through the night. The fact that you're finding it exceeds your expectations and stands out compared to other products you've tried is exactly the kind of validation that shows we're delivering something special for lip care!
We hear you on the applicator feedback, and we genuinely appreciate your honesty about wishing it had a longer handle and more paddle-shaped design for easier handling. That kind of constructive input really helps us understand how our products work in real life, and we're grateful you're taking the time to share it with us.
Thank you for taking the time to share such encouraging feedback about your OS-01 LIP MASK experience - your 4-star review truly means so much to us!
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- JS
Jovita S.
Verified Reviewer
Reviewing
OS-01 LIP MASK
I recommend this product
Rated 5 out of 5 stars
1 week ago
My go to night lip mask
I was actually a bit sceptical about this lip mask at first. The texture is a bit firmer than what I had used previously, and I wasn't using it consistently. My initial thought was, "I'll just finish it and probably won't buy it again," because I didn't notice much of a difference. Then I started using it every night (mostly because I wanted to finish it faster), and after about a week I realised my lips looked different in the morning. They felt noticeably plumper and much more hydrated. I also started to appreciate that once you go to sleep, you don't really feel the product on your lips, so your pillowcase stays free from lip mask stains!
Now that I'm almost out of it, I'm literally scraping every last bit from the jar, and I've realised this is the night lip mask for me. No irritating ingredients, no stains on my pillowcase, and the morning plumpness is amazing. I absolutely love lip products and I'm always trying new ones, but I don't think I'll be changing my night lip mask anymore. By the way, I understand that the included applicator is probably a more environmentally friendly option, but I just can't get used to it. I either apply the mask with my fingers or use the silicone applicator from another lip product. It might not bother everyone, but personally I think a silicone applicator would be a much better choice.
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OneSkin
1 week ago
Hi Jovita!
Thank you so much for this wonderful review — and we love that you've become a true believer in OS-01 LIP MASK! It's so rewarding to hear that you gave it a real chance and discovered what it could do for your lips when used consistently. The fact that you're now scraping every last bit from the jar tells us everything we need to know!
We're thrilled that you're experiencing that morning plumpness and hydration you were hoping for, and we completely get the appeal of a product that works its magic overnight without leaving stains on your pillowcase. That's such a practical benefit that makes a real difference to your routine.
We really appreciate your honest feedback about the applicator as well. We hear you on the texture preference, and it's genuinely valuable to know that a silicone applicator would feel like a better fit for you personally. Your suggestion is something we'll make sure gets passed along to our team — understanding what would make the experience even better for our customers helps us continue to refine every detail.
Thank you so much for sticking with OS-01 LIP MASK long enough to discover how amazing it could be for your lips, and thank you for choosing OneSkin!
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