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[SHOP NOW](/content/collections/all-products/index.html) Icon For Close Icon For Search Clear View all results # OS-01 FACE MOISTURIZER 4.7 4.7 out of 5 [4.7(6,468 reviews)(6.4K)](/content/products/01-face-topical-supplement?variant=44012708888835#okendo-reviews/index.html) 50 mL / 1.7 fl oz OS-01 # FACE MOISTURIZER 4.7★ [(6,468 reviews)](/content/products/01-face-topical-supplement?variant=44012708888835#okendo-reviews/index.html) Lightweight hydration, clinically shown to firm and smooth skin. HydratingSmoothingFragrance-free OS-01 # FACE MOISTURIZER ## Lightweight hydration, clinically shown to firm and smooth skin. 4.7 4.7 out of 5 [4.7(6,468 reviews)(6.4K)](/content/products/01-face-topical-supplement?variant=44012708888835#okendo-reviews/index.html) 4.7 4.7 out of 5 [4.7(6,468 reviews)(6.4K)](/content/products/01-face-topical-supplement?variant=44012708888835#okendo-reviews/index.html) 50 mL / 1.7 fl oz HydratingSmoothingFragrance-free [Starter Kit](/content/products/01-face-topical-supplement/index.html) [Refill](/content/products/os-01-face-refill-pouch-one-time-purchase/index.html) [STARTER SET\\ \\ 50 mL / 60 uses per bottle](/content/products/01-face-topical-supplement/index.html) [REFILL\\ \\ 50 mL / 60 uses per pod](/content/products/os-01-face-refill-pouch-one-time-purchase/index.html) Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01 - Boosts hydration, elasticity, and barrier function - 96% showed an improvement in firmness and radiance - Dermatologist tested, fragrance-free, safe for sensitive skin One-time purchase Subscribe SAVE 15% EVERY ORDER Subscribe Delivery every 1 month Delivery every 2 months (Most popular) - Exclusive early access to new products - Earn 2x points on all recurring orders - Easily change, skip or cancel anytime LIMITED TIME OFFER Travel-size OS-01 EYE with your first subscription $38FREE Delivered every month $117$100 Subscribe and save 15% - Exclusive early access to new products - Earn 2x points on all recurring orders - Easily change, skip or cancel anytime Recommended Delivered every 2 monthsRecommended $117$100 Subscribe and save 15% - Exclusive early access to new products - Earn 2x points on all recurring orders - Easily change, skip or cancel anytime LIMITED TIME OFFER Travel-size OS-01 EYE with your first subscription $38FREE One-time purchase $117 Quantity Default Title ADD TO CART $117$100 Icon For Checkmark Quantity selected exceeds current stock Free shipping on orders over $79.00 USD Try it risk-free for 30 days! You’re earning 99 points with the OneSkin Loyalty Program Free shipping on orders $79+ ### You’re earning 99 points with OneSkin Loyalty Program Details− - Powered by the proprietary OS-01 Peptide™, works where aging begins for skin that looks and feels younger and healthier over time - Lightweight, instantly hydrating, and compatible with any routine or skin type. - Clinically shown to deliver smoother, firmer, more even-toned skin in 12 weeks.¹ - Builds a healthy, resilient foundation that helps every other product and treatment in your routine perform better. Clinical proof+ A 12-week, third-party split-face clinical study demonstrated that OS-01 FACE MOISTURIZER significantly improves skin smoothness, firmness, radiance, and elasticity. Published in the Journal of Cosmetic Dermatology. [Explore the clinical studies →](/content/pages/science/index.html) Ingredients+ Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. #### Ingredients Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52\*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. \*OS-01 Peptide. How to use+ Dispense 1–2 pumps onto your fingers and gently massage into the face and neck. Use twice daily, morning and evening. ## Complete the protocol ### OS-01 EYE CREAM ★★★★★4.8 Firm and hydrate the delicate skin around the eyes. ADD TO CART — $109 ### OS-01 BODY MOISTURIZER ★★★★★4.8 Revive thin, crepey skin with our daily body moisturizer. ADD TO CART — $105 Clean + Safe Ingredients Our products are non-comedogenic (non-pore clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents. - - - - Adding product to your cart Benefits ## Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment ### Hydration Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02 ### Firmness Switches off the cells that degrade collagen, helping skin stay firm.01,03 ### Radiance Enhances skin tone and texture, helping skin look and feel smooth and radiant.02 Pause 5-STAR REVIEWS ## See why customers love OS-01 FACE ### “I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N. ### "I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E. ### "It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C. ### "One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B. ## The proof is in the pictures CLINICAL DATA ## Visible results, scientifically validated ### 100 of participants had improved smoothness 02 ### 96 of participants had improved firmness, radiance, and tone 02 ### 90 of participants had improved elasticity 02 ### 86 of participants had improved appearance of fine lines and wrinkles 02 ## 6 active ingredients that complement the OS-01 peptide [see all ingredients](/content/products/01-face-topical-supplement?variant=44012708888835#all-ingredients/index.html) ### Pracaxi Oil Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties. ### Andiroba Oil A seed oil that promotes healthy collagen and minimizes the effects of inflammation. ### Niacinamide A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer. ### Oleic Pau Mulato Extract An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing. ### Allantoin A skin-conditioning molecule that moisturizes and soothes irritated skin. ### Hyaluronic Acid A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin. Pause ## Getting started with OS-01 FACE Follow these easy steps for optimal results - Dispense 1-2 pumps onto fingers - Gently massage into skin on the face and neck - Use 2 times daily Your browser does not support the video tag. Pause How it works ## Powered by the OS-01 Senescence Blocking Peptide™ The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 [Discover the Science](/content/pages/science/index.html) ### All Ingredients ### Citations 01 Zonari, A., _et al._ Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. _npj Aging_, 9(1), 1-15. 2023. doi: [10.1038/s41514-023-00109-1](https://doi.org/10.1038/s41514-023-00109-1) 02 Zonari A., _et al._ Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. _J Cosmet Dermatol._ 2024; 23: 2135-2144. doi: [10.1111/jocd.16242](https://doi.org/10.1111/jocd.16242) 03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at [oneskin.co/claims](/content/claims/index.html) ## OS-01 FACE MOISTURIZER 4.7 Rated 4.7 out of 5 stars Based on 6,468 reviews 5 Rated out of 5 stars 5.3k Total 5 star reviews: 5.3k 4 Rated out of 5 stars 816 Total 4 star reviews: 816 3 Rated out of 5 stars 259 Total 3 star reviews: 259 2 Rated out of 5 stars 75 Total 2 star reviews: 75 1 Rated out of 5 stars 67 Total 1 star reviews: 67 **94%** would recommend these products Reviews 6,468(tab expanded) Questions 100(tab collapsed) Filters [Write a Review (Opens in a new window)](https://okendo.reviews/?subscriberId=24856cd3-9a87-4f95-92df-dff37c688881&productId=shopify-8098469773571&locale=en&okeChannel=reviews-widget-write-review-button) 6,468 reviews Sort Most RecentPhotos & VideosMost HelpfulHighest RatingOldestLowest RatingLeast Helpful - **SG** **Sarah G.** Verified Buyer Reviewing OS-01 FACE Refill Pouch I recommend this product Rated 5 out of 5 stars 4 minutes ago Love the packaging I appreciate the packaging of the OS-01 Face. Read MoreRead more about this review Was this helpful? Yes, this review from Sarah G. was helpful. 0 people voted yesNo, this review from Sarah G. was not helpful. 0 people voted no - **SM** **Susan M.** Verified Buyer Reviewing OS-01 FACE Refill Pouch I recommend this product Rated 5 out of 5 stars Yesterday OS-01 Pouch I love the re-fill pouch! Super easy to remove/install and not a waist! Easy-Peasy! Read MoreRead more about this review Was this helpful? Yes, this review from Susan M. was helpful. 0 people voted yesNo, this review from Susan M. was not helpful. 0 people voted no - **P** **Peter** Reviewing OS-01 FACE Refill Pouch I recommend this product Rated 4 out of 5 stars 2 days ago 4 Stars I like this product but ive just learmed that facial creams etc…should be in glass containers to ensure their integrity. Read MoreRead more about this review Was this helpful? Yes, this review from Peter was helpful. 0 people voted yesNo, this review from Peter was not helpful. 0 people voted no - **LK** **Linda K.** Verified Buyer Reviewing OS-01 FACE Refill Pouch I recommend this product Rated 5 out of 5 stars 2 days ago Love this face lotion My and my husband both use this product and love the silky and light feel on our face. Thank you One Skin! Read MoreRead more about this review Was this helpful? Yes, this review from Linda K. was helpful. 0 people voted yesNo, this review from Linda K. was not helpful. 0 people voted no - **NJ** **Nancy J.** Verified Buyer Reviewing OS-01 FACE Refill Pouch I recommend this product Rated 5 out of 5 stars 2 days ago OS-01 - Refill this refill is easy to slip back into the case and I love this product. Read MoreRead more about this review Was this helpful? Yes, this review from Nancy J. was helpful. 0 people voted yesNo, this review from Nancy J. was not helpful. 0 people voted no Loading... Loading... 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